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Paroxetine-clomipramine

224 bytes removed, 15:48, 28 October 2015
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| to = clomipramine
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* '''Before day 1:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day. * '''Day 1:''' reduce dosage of paroxetine to a maximum of 10 mg/day. * '''Day 8:''' stop dosage of paroxetine.{{stopParoxetine}}
| start =
Caution is necessary.
* '''Day 89:''' start administration of clomipramine in a low dosage of 25-50 mg/day. * '''Day 1516:''' increase dosage of clomipramine to 50-100 mg/day.* '''Day 2829:''' if necessary, increase dosage of clomipramine.
| info =
* Paroxetine slows the metabolism of clomipramine via CYP2D6.
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