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Doxepine-bupropion

201 bytes removed, 16:12, 28 October 2015
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* '''Before day 1:''' gradually reduce dosage of doxepin to a maximum of 100 mg/ day, when this dosage is > 100 mg/day.* '''Day 1-3:''' reduce dosage of doxepin to 50 mg/day.* '''Day 4-7:''' reduce dosage of doxepin to 25 mg/day.{{stopDoxepin}}
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* '''Day 48:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of doxepin according to the scheme above.* '''Day 815:''' stop administration of doxepin and continue administration of bupropion.* '''Day 1523:''' if necessary increase the dosage of bupropion.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes doxepin.
* {{RiskSeizureBupropionTCA}}
}}
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