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Dosulepine-fluvoxamine

315 bytes removed, 13:10, 2 November 2015
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* '''Before day 1:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.* '''Day 7:''' stop administration of dosulepine{{stopDosulepine}}
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* '''Day 89:''' start administration of fluvoxamine in a normal dosage of 50 mg/day.
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}
* Fluvoxamine is an inhibitor of CYP1A2, CYP2C19 and CYP3A4 (moderate), which metabolize dosulepine.
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