| to = sertraline
| stop =
* '''Before day 1:''' gradually reduce dosage of nortriptyline to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of nortriptyline to 50 mg/day.* '''Day 3:''' reduce dosage of nortriptyline to 25 mg/day.{{downNortriptyline}}
| start =
* '''Day 1:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
| info =
* Sertraline is a weak inhibitor of [[:wp:CYP2D6|CYP2D6]], which metabolizes nortriptyline.
{{review}}
}}