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* '''Day 0:''' gradually reduce dosage of doxepin amitriptyline to a maximum of 100 mg/ day, when this dosage is > 100 mg/day.* '''Day 1-3:''' reduce dosage of doxepin amitriptyline to 50 mg/day.* '''Day 4-7:''' reduce dosage of doxepin amitriptyline to 25 mg/day.* '''Day 8:''' stop administration of doxepin.
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* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of amitriptyline according to the scheme above.
