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Duloxetine-vortioxetine

218 bytes removed, 12:29, 4 November 2015
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| to = vortioxetine
| stop =
* '''Before day 1:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/day, when this dosage is > 60 mg/day. * '''Day 1:''' reduce dosage of duloxetine from 60 mg/day to 30 mg/day.* '''Day 8:''' stop duloxetine.{{stopDuloxetine}}
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* A wash-out period of 3 days is advisable.
* '''Day 1112:''' Start administration of vortioxetine in a dosage of 10 mg/day.
| info =
* Duloxetine is an inhibitor of CYP2D6, which metabolizes vortioxetine.
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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