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Created page with '{{Drugswitch | from = maprotiline | to = bupropion | stop = * '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/ day, when this dosage is > 75 ...'
{{Drugswitch
| from = maprotiline
| to = bupropion
| stop =
* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.
* '''Day 1-3:''' reduce dosage of maprotiline to 50 mg/day.
* '''Day 4-7:''' reduce dosage of maprotiline to 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of maprotiline according to the scheme above.
* '''Day 8:''' stop administration of maprotiline and continue administration of bupropion only in a dosage of 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes doxepin. }}
| from = maprotiline
| to = bupropion
| stop =
* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.
* '''Day 1-3:''' reduce dosage of maprotiline to 50 mg/day.
* '''Day 4-7:''' reduce dosage of maprotiline to 25 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of maprotiline according to the scheme above.
* '''Day 8:''' stop administration of maprotiline and continue administration of bupropion only in a dosage of 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes doxepin. }}
