* Plasma monitoring for TCA's is advisable, because of plasma-reponse relations, genetic polymorphism and under/or overdosing.<ref name="Plasma monitoring of TCA's">https[http://tdm-monografie.org/monografie/tca-tricyclische-antidepressiva (dutch) monografie .org tricyclische-antidepressiva bloedspiegelbepalingen(Dutch)]</ref><noinclude><references /></noinclude>