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* '''Day 1:''' simultaneously start fluoxetine in a normal dosage of 20 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of fluoxetine only.
* If necessary, increase the dosage of fluoxetine. | info = * Fluoxetine is a strong inhibitor of CYP2D6, which metabolizes mianserine, so caution is necessary. }}