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* '''Day 2: ''' Start administration of clomipramine in a normal dosage of 50-75 mg/day.
* Increase the dose with about 25% of the target dose every 3 days.
* Therapeutic Drug Monitoring of clomipramine is useful, especially during the build up phase. Blood sampling is possible when reaching a steady state with the same dose after one week.
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* A wash-out period is not necessary.
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