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Created page with '{{Drugswitch | from = mianserine | to = duloxetine | stop = * '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. * '''Day 1:''' reduce a dosage of...'
{{Drugswitch
| from = mianserine
| to = duloxetine
| stop =
* '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start duloxetine in a low dosage of 30 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of duloxetine.
* If necessary, increase the dosage of duloxetine.
| info =
* Caution with this switch is necessary, because duloxetine slows the metabolism of mianserine via CYP2D6. }}
| from = mianserine
| to = duloxetine
| stop =
* '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start duloxetine in a low dosage of 30 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of duloxetine.
* If necessary, increase the dosage of duloxetine.
| info =
* Caution with this switch is necessary, because duloxetine slows the metabolism of mianserine via CYP2D6. }}
