Changes

| stop = {{generaldecrease25p3d}}* Decrease with about 25% of original dose every 3-4 days

* '''Day 91:''' start administration of maprotiline nortriptyline in a low dosage of 25 mg/day. * '''Day 16Stop paroxetine:''' increase administration of maprotiline nortriptyline to a dosage of 50-100 mg/day.

* "Start low, go slow" is not required, but caution is necessary!* Paroxetine slows the metabolism of maprotiline nortriptyline via CYP1A2 and CYP2D6.