* '''Day 1:''' simultaneously | start administration of paroxetine in a low dosage of 10 mg/day.* '''Day 8:''' stop administration of nortriptyline and continue administration of paroxetine in a dosage of 20 mg/day.= {{StartAntidepressant}}
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* Paroxetine is a strong inhibitor of [[wp:CYP2D6|CYP2D6]], which metabolizes nortriptyline. * Safe target dose paroxetine is 20 mg
