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{{Drugswitch Drugswitchago
| from = fluvoxamine
| to = agomelatine
| stop =
{{stopFluvoxamine}}
| start = * '''Day 8-14:''' a wash-out period of one week is necessary.* '''Day 15:''' start administration of agomelatine after this period in a dosage of 25 mg/day.* ''' Day 22: ''' if necessary, the dosage of agomelatine can be increased to 50 mg/day.{{StartAgomelatine}}
| info =
* Fluvoxamine inhibits the metabolism of agomelatine via CYP1A2 (90%) and via CYP2C9/2C19 (10%).<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>
{{SSRI14d}}
}}
