Difference between revisions of "Combining-Quetiapine-Lamotrigine"
From Psychiatrienet
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* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination. | * This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination. | ||
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Latest revision as of 08:35, 22 April 2010
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Adding lamotrigine to quetiapine.
General information- Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
- Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
- This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
Start lamotrigine- Start lamotrigine according to the general dosing advice.
- ↑ 1.0 1.1 1.2 KNMP; Informatorium Medicamentorum 2023; Monografie "quetiapine" (Dutch)
- ↑ NVZA; Toxicology.org; Monografie 73 (dutch)
- ↑ Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
- ↑ 4.0 4.1 Drugs.com quetiapine-fumarate Cite error: Invalid
<ref>tag; name "drugscom" defined multiple times with different content - ↑ Farmacotherapeutisch Kompas; Toxicologie (dutch)
- ↑ Farmacotherapeutisch Kompas - lamotrigine (dutch)
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