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* '''Before day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of sertraline to 25 mg/day.
* '''Day 8:'''stop administration of sertraline.
| start =
* No wash-out period is needed.
* '''Day 9:''' start duloxetine the next day in normal dosage of 60 mg/day.}}