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| start =
* '''Day 1-7:''' a wash-out period of at least one week is necessary.
* '''Day 8:''' start paroxetine the next day in low dosage of 10 with 20 mg/day.
| info =
* By considering a wash-out period of one week (5 times the elimination time of bupropion and its metabolites) it is assured that all bupropion has left the body and no drug interactions occur.
* Bupropion slows the metabolismof paroxetine by CYP2D6.}}
