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| start =
* '''Day 1:''' simultaneously start administration of bupropion in a dosage of 150 mg/day and continue administration of amitriptyline according to the scheme above.
* '''Day 8:''' stop administration of amitriptyline and continue administration of bupropion only in a dosage of 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes amitriptyline. }}
