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* Start administration of imipramine the next day in a dosage of 25-75 mg/day.
* If necessary, gradually increase dosage of imipramine to 150-200 mg/day under monitoring of bloodlevel.
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>
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