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Agomelatine-fluvoxamine

307 bytes removed, 13:38, 5 March 2010
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| from = agomelatine
| to = fluvoxamine
| stop = * Gradually reduce dosage of agomelatine to a maximum of 25 mg/day. * When a dosage of 25 mg/day is reached , stop administration.{{StopAgomelatine}}
| start =
* A wash-out period of one day is necessary.
| info =
* Fluvoxamine stops the metabolism of agomelatine via CYP1A2 and CYP2C9.
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>
}}
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