Open main menu

Psychiatrienet β

Changes

Combining-Valproic acid-Risperidone

569 bytes added, 17:14, 5 March 2010
Created page with '{{Drugcombi | base = valproic acid | add = risperidone | info = * Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic ...'
{{Drugcombi
| base = valproic acid
| add = risperidone
| info =
* Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
*
| cave =
}}
387
edits