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Fluoxetine-tranylcypromine

653 bytes added, 20:47, 3 May 2009
Created page with '{{Drugswitch | from = fluoxetine | to = tranylcypromine | stop = * Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a...'
{{Drugswitch
| from = fluoxetine
| to = tranylcypromine
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
* When a dosage of 20 mg/day is reached, stop administration.
| start =
Caution is necessary.
* '''Day 1-35:''' a wash-out period of five weeks is necessary.
* '''Day 36:''' start tranylcypromine the next day in a normal dosage of 20 mg/day.
| info =
* A switch from fluoxetine to tranylcypromine is not obvious, given the necessary prolonged wash-out period in this case.
* Occurrence of serotonin syndrome is reported when a wash-out period (of five weeks) is not considered.}}
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