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Caution is necessary.
* '''Day 1-35:''' a wash-out period of five weeks is necessary.
* '''Day 36:''' start tranylcypromine the next day in a normal low dosage of 20 mg/dayfor one week.* '''Day 43:''' after this week the dosage of tranylcypromine can be increased if necessary.
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* A switch from fluoxetine to tranylcypromine is not obvious, given the necessary prolonged wash-out period in this case.
* Occurrence of serotonin syndrome is reported when a wash-out period (of five weeks) is not considered.}}