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Created page with '{{Drugswitch | from = duloxetine | to = maprotiline | stop = * '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day. * '''Day 1:''' reduce the ...'
{{Drugswitch
| from = duloxetine
| to = maprotiline
| stop =
* '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day.
* '''Day 1:''' reduce the dosage of duloxetine to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of duloxetine and increase the dosage of maprotiline to 50 mg/day.
| info =
* Duloxetine slows the metabolism of maprotiline by CYP2D6.
* Caution is necessary at the start of administration of maprotiline. }}
| from = duloxetine
| to = maprotiline
| stop =
* '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day.
* '''Day 1:''' reduce the dosage of duloxetine to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of duloxetine and increase the dosage of maprotiline to 50 mg/day.
| info =
* Duloxetine slows the metabolism of maprotiline by CYP2D6.
* Caution is necessary at the start of administration of maprotiline. }}
