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Bupropion-fluoxetine

10 bytes removed, 15:25, 7 October 2015

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| to = fluoxetine

| stop =

* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion1}}

| start =

*''' Day 2:''' * Start fluoxetine the next day in normal dosage of 20 mg/day.

* ''' After 3 weeks:''' If necessary, increase the dosage gradually to 40-60 mg/day.

| info =

* No wash-out period is needed.

* Start fluoxetine the next day in normal dosage of 20 mg/day.

~~| info =~~

* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.

* Bupropion slows the metabolism of fluoxetine by CYP2D6.

* {{2D6NRI}}

}}

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