| to = imipramine
| stop =
{{stopSertralineTCAdecrease25p3d}}
| start =
Caution is necessary.* '''Day 1:''' simultaneously start administration of imipramine in a low dosage of 25 mg/day. * '''Day 8:''' stop administration of sertraline and only continue administration of imipramine in a dosage of 50 mg/day.* Start low, go slow!{{TCAincrease25p3d}}| info = * Sertraline dose-dependently slows the metabolism of imipramine via CYP2C9 and CYP2D6. * {{theorSSTCAplasmalevelmonitoring}}
}}