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Created page with '{{Drugswitch | from = mianserine | to = sertraline | stop = * '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. * '''Day 1:''' reduce a dosage of ...'
{{Drugswitch
| from = mianserine
| to = sertraline
| stop =
* '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of sertraline only.
* If necessary, increase the dosage of sertraline.
| info =
* Caution with this switch is necessary, because sertraline dose-dependently slows the metabolism of mianserine via CYP2D6. }}
| from = mianserine
| to = sertraline
| stop =
* '''Day 0:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of sertraline only.
* If necessary, increase the dosage of sertraline.
| info =
* Caution with this switch is necessary, because sertraline dose-dependently slows the metabolism of mianserine via CYP2D6. }}
