838
edits
Changes
no edit summary
| start =
* '''Day 1:''' simultaneously start sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of mianserine and only continue administration of sertraline only.
* If necessary, increase the dosage of sertraline.
| info =
* Caution with this switch is necessary, because sertraline dose-dependently slows the metabolism of mianserine via CYP2D6. }}