SwitchAntipsychotics

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Switching Antipsychotics

To see the consequences of a switch between antipsychotics click in the crosstable below: the switch is made "from" (vertical) "to" (horizontal).
During switching: don't reduce dose of other anticholinergic drugs; consider adding oxazepam. Read: General considerations concerning switching antipsychotics.


Rest AP = Chlorprothixene, Flupentixol, Loxapine, Paliperidone, Pericyazine, Perphenazine,Promazine, Trifluoperazine, Zuclopentixol.

Partial antagonist = Aripiprazole, Brexpiprazole, Cariprazine.


 from to → Am Ch Cp Hp Lu Ol Pa Pi Qu Rd Sd Sr Zi RA Da Df Di Dh Do Dp Dr Dz Mz
Am Amisulpride  — AmCh AmCp AmHp AmLu AmOl AmPa AmPi AmQu AmRd AmSd AmSr AmZi AmRA AmDa AmDf AmDi AmDh AmDo AmDp AmDr AmDz AmMz
Ch Chlorpromazine ChAm  — ChCp ChHp ChLu ChOl ChPa ChPi ChQu ChRd ChSd ChSr ChZi ChRA ChDa ChDf ChDi ChDh ChDo ChDp ChDr ChDz ChMz
Cp Clozapine CpAm CpCh  — CpHp CpLu CpOl CpPa CpPi CpQu CpRd CpSd CpSr CpZi CpRA CpDa CpDf CpDi CpDh CpDo CpDp CpDr CpDz CpMz
Hp Haloperidol HpAm HpCh HpCp  — HpLu HpOl HpPa HpPi HpQu HpRd HpSd HpSr HpZi HpRA HpDa HpDf HpDi HpDh HpDo HpDp HpDr HpDz HpMz
Lu Lurasidone LuAm LuCh LuCp LuHp  — LuOl LuPa LuPi LuQu LuRd LuSd LuSr LuZi LuRA LuDa LuDf LuDi LuDh LuDo LuDp LuDr LuDz LuMz
Ol Olanzapine OlAm OlCh OlCp OlHp OlLu  — OlPa OlPi OlQu OlRd OlSd OlSr OlZi OlRA OlDa OlDf OlDi OlDh OlDo OlDp OlDr OlDz OlMz
Pa Partial antagonist new PaAm PaCh PaCp PaHp PaLu PaOl PaPa PaPi PaQu PaRd PaSd PaSr PaZi PaRA PaDa PaDf PaDi PaDh PaDo PaDp PaDr PaDz PaMz
Pi Pimozide PiAm PiCh PiCp PiHp PiLu PiOl PiPa  — PiQu PiRd PiSd PiSr PiZi PiRA PiDa PiDf PiDi PiDh PiDo PiDp PiDr PiDz PiMz
Qu Quetiapine QuAm QuCh QuCp QuHp QuLu QuOl QuPa QuPi  — QuRd QuSd QuSr QuZi QuRA QuDa QuDf QuDi QuDh QuDo QuDp QuDr QuDz QuMz
Rd Risperidone RdAm RdCh RdCp RdHp RdLu RdOl RdPa RdPi RdQu  — RdSd RdSr RdZi RdRA RdDa RdDf RdDi RdDh RdDo RdDp RdDr RdDz RdMz
Sd Sertindole SdAm SdCh SdCp SdHp SdLu SdOl SdPa SdPi SdQu SdRd  — SdSr SdZi SdRA SdDa SdDf SdDi SdDh SdDo SdDp SdDr SdDz SdMz
Sr Sulpiride SrAm SrCh SrCp SrHp SrLu SrOl SrPa SrPi SrQu SrRd SrSd  — SrZi SrRA SrDa SrDf SrDi SrDh SrDo SrDp SrDr SrDz SrMz
Zi Ziprasidone ZiAm ZiCh ZiCp ZiHp ZiLu ZiOl ZiPa ZiPi ZiQu ZiRd ZiSd ZiSr  — ZiRA ZiDa ZiDf ZiDi ZiDh ZiDo ZiDp ZiDr ZiDz ZiMz
RA Rest AP RAAm RACh RACp RAHp RALu RAOl RAPa RAPi RAQu RARd RASd RASr RAZi RARA RADa RADf RADi RADh RADo RADp RADr RADz RAMz
Da Aripiprazole_LA DaAm DaCh DaCp DaHp DaLu DaOl DaPa DaPi DaQu DaRd DaSd DaSr DaZi DaRA  — DaDf DaDi DaDh DaDo DaDp DaDr DaDz DaMz
Df Fluphenazine_LA DfAm DfCh DfCp DfHp DfLu DfOl DfPa DfPi DfQu DfRd DfSd DfSr DfZi DfRA DfDa  — DfDi DfDh DfDo DfDp DfDr DfDz DfMz
Di Flupenthixol_LA DiAm DiCh DiCp DiHp DiLu DiOl DiPa DiPi DiQu DiRd DiSd DiSr DiZi DiRA DiDa DiDf  — DiDh DiDo DiDp DiDr DiDz DiMz
Dh Haloperidol_LA DhAm DhCh DhCp DhHp DhLu DhOl DhPa DhPi DhQu DhRd DhSd DhSr DhZi DhRA DhDa DhDf DhDi  — DhDo DhDp DhDr DhDz DhMz
Do Olanzapine_LA DoAm DoCh DoCp DoHp DoLu DoOl DoPa DoPi DoQu DoRd DoSd DoSr DoZi DoRA DoDa DoDf DoDi DoDh  — DoDp DoDr DoDz DoMz
Dp Paliperidone_LA DpAm DpCh DpCp DpHp DpLu DpOl DpPa DpPi DpQu DpRd DpSd DpSr DpZi DpRA DpDa DpDf DpDi DpDh DpDo  — DpDr DpDz DpMz
Dr Risperidone_LA DrAm DrCh DrCp DrHp DrLu DrOl DrPa DrPi DrQu DrRd DrSd DrSr DrZi DrRA DrDa DrDf DrDi DrDh DrDo DrDp  — DrDz DrMz
Dz Zuclopenthixol_LA DzAm DzCh DzCp DzHp DzLu DzOl DzPa DzPi DzQu DzRd DzSd DzSr DzZi DzRA DzDa DzDf DzDi DzDh DzDo DzDp DzDr  — DzMz
Mz Zuclopenthixol_MA MzAm MzCh MzCp MzHp MzLu MzOl MzPa MzPi MzQu MzRd MzSd MzSr MzZi MzRA MzDa MzDf MzDi MzDh MzDo MzDp MzDr MzDz  —

LA = long acting, MA = medium acting

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